HIV Type 1 and Cytomegalovirus Coinfection in the Female Genital Tract

Mucosal Immunity in the Female Genital Tract, HIV/AIDS

Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmission, with an increased risk of infection in women compared to men. Several ch...

Genital tract leukocytes and shedding of genital HIV type 1 RNA.

BACKGROUND The mechanism of human immunodeficiency virus (HIV) transmission via heterosexual intercourse is unknown. We sought to determine whether the presence of inflammatory cells in the vagina is associated with the presence of genital tract HIV type 1 (HIV-1) RNA. METHODS Analysis of a longitudinal prospective cohort was performed. Women with HIV-1 infection were assessed with use of pai...

Female Genital Tract Tumors

Female Genital Tract Cysts

Cystic diseases in the female pelvis are common. Cysts of the female genital tract comprise a large number of physiologic and pathologic cysts. The majority of cystic pelvic masses originate in the ovary, and they can range from simple, functional cysts to malignant ovarian tumors. Non-ovarian cysts of female genital system are appeared at least as often as ovarian cysts. In this review, we aim...

Correlation of human immunodeficiency virus type 1 RNA levels in blood and the female genital tract.

In this study, the correlations of human immunodeficiency virus type 1 (HIV-1) RNA levels in blood plasma, vaginal secretions, and cervical mucus of 52 HIV-1-infected women were determined. The amount of cell-free HIV-1 RNA in blood plasma was correlated with that in vaginal secretions (Spearman's rank correlation coefficient (r) = 0.64, P<.001). In both blood plasma and vaginal secretions, the...